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(1) In patients with correctible or temporary causes of vitamin B12 deficiency the benefit of continued long-term use following correction of vitamin B12 deficiency and underlying disease has not been established

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The de novo synthesis of GSH takes place in the cytosol of human cells and involves two sequential ATP-dependent enzymatic reactions 9

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Low B12 levels can slow metabolism and cause fatigue, making it harder to stay active, which may contribute to weight gain