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Sina Gallo , Jung Sun Lee , Caree Cotwright , and colleagues have a paper in press in the Journal of Nutrition Education and Behavior

This molecular engineering has created a powerful research tool that preserves the natural pulsatile growth hormone release patterns essential for physiological function while extending the peptide's biological activity to 30 minutes to 2 hours, compared to mere minutes for endogenous GHRH

The 60% power contemplated requires a sample size of 304 patients (152 in each arm) higher powers would increase the sample size required and the enrolment of such numbers cannot be guaranteed