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At day 0, 4 and 8, female C57/BL6 mice (Janvier Labs, Le Genest-Saint-lsle, France) were lightly anesthetized with isoflurane and intranasally administered with 20 pL of 1 mg/kg bleomycin PBS solution (Bleomycine Bellon, 15 mg for injection) or PBS (negative control mice)

Rose Hips are a rich source of Vitamin C and other antioxidants, while Bioflavonoids are natural compounds that help to boost the absorption of Vitamin C

Vitamin C in its pure ascorbic acid form degrades quickly when exposed to air, light, and heat

By boosting NAD+ levels, this therapy can enhance mental clarity, improve energy, and promote healthy aging while aiding in recovery from fatigue and stress

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All statistical analyses were performed using SigmaPlot v.12