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Bacterial overgrowth syndrome is a disorder in which poor intestinal motility allows certain intestinal bacteria to grow excessively, causing diarrhea and malabsorption

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Adverse Events FDA received an adverse event report on January 14, 2019, regarding seven patients in an outpatient clinic who received intravenous injections containing L-glutathione 200mg/mL compounded by a pharmacy using L-glutathione repackaged by Letco (lot number: 1810150050, expiration date: 6/17/2020)

An intranasal spray solution of B12, also called Nascobal, with the same indications, was FDA approved in January 2005

It was also reported for its beneficial effect in Phase III clinical trial for type 2 diabetes and stage 4 chronic kidney disease patients, where it was shown to improve the estimated glomerular filtration rate (GFR) ( , a nutritional supplement containing five natural Nrf2 activators such as bacosides, silymarin, withanolides, ECGC and curcumin has been shown to reduce oxidative stress and increase antioxidant enzymes SOD and catalase expression (Nelson et al., 2006)

It remains prohibited under the 2026 Prohibited List