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Description

This can protect sensitive thiols from irreversible oxidation and contribute to cellular signalling

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Poor Glutathione Status and Difficulty With TTFD In someone who has poor glutathione (GSH) status, they might theoretically be less able to cleave thiamine from TTFD

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Ethics statement The studies involving humans were approved by Public data from ADNI, no need for ethical approval again

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10.1021/acschembio.2c00914 326 ZhuJ.SunR.YanC.SunK.GaoL.ZhengB.et al (2023a)

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However, the mutations in the p53 DBD lead to disruption in the ability to bind this RE

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