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To reduce intracellular Fe 3+ levels and prevent its conversion to Fe 2+ , iron chelators are widely employed

doi:10.3390/ijms23010119 29

doi: 10.1155/2018/8063647 215 Maldonado GaldeanoCCazorlaSILemme DumitJMVlezEPerdignG

It has been suggested that the oxidative DNA damage and the immunologic responses it evokes (autoantibodies) start occurring not only in the carcinogenic process [36] but also in various autoimmune diseases [40, 36, 37, 39, 38]

Acknowledgments Figures were created using BioRender (publication licenses: and and Datawrapper ( Guo X.Y., Song D.Y., Wu M.Y., Zhang J.Q., Li J.Y., and Yuan L., Parkinson's Disease: The Epidemiology, Risk Factors, Molecular Pathogenesis, Prevention, and Therapy. MedComm 6, no

doi: 10.1186/s12879-020-05349-0 157 YangX.ShuiY.QianY