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About this article Cite this article Adwani, G., Bharti, S

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Glutathione transferase pi plays a critical role in the development of lung carcinogenesis following exposure to tobacco-related carcinogens and urethane

Cytosolic Ca 2 dynamics are finely regulated by influx from intracellular organelles (vacuole, endoplasmic reticulum, mitochondria, plastids) and the plasma membrane via voltage-dependent, mechanosensitive, or ligand-activated channels, whereas efflux is mediated by Ca 2 -ATPases and Ca 2 /H antiporters

Even recent anti-amyloid immunotherapies, while targeting one of the core pathologies of AD, have shown limited clinical benefit and raised concerns regarding safety, efficacy, and applicability across the disease spectrum