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The 1 mg arm of Phase 2 produced direct measurement

Patients typically report increased mental clarity, reduced fatigue, and a sense of physical lightness early in the protocol

After 2 years of treatment, when compared with females taking the placebo, females taking Prolia had BMD that was increased by: 7.6% in their spine 4.7% in their hip 3.6% in their femoral neck (the upper part of the thigh bone that connects into the hip) Off-label uses for Prolia In addition to the uses listed above, Prolia may be used off-label

Titrate: Increase to 200 mcg daily if tolerated and necessary [5]

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