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doi: 10.3389/fimmu.2019.00277 103

In the MYO among upregulated DEGs detected in MYO-1, two were related to mechanisms associated with cellular/endoplasmic reticulum stress: Scd2, described above, and Hspb1 (Heat Shock Protein Family B (Small) Member 1) involved in AMPK/HSPB1-mediated inhibition of inflammation and ER stress in skeletal muscle under hyperlipidemic conditions 46

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Hence, BSO-OxMal avoids renal DNA damage despite the suppression of GSH synthesis by BSO, impressively confirming the excellent tumor-targeting of this drug

Sure, dietary exposure to mercury may harm child development, but if we cut down on fish, the argument goes, we could get fewer omega-3s