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each diet group was then administered corn oil (control) or fluorene (50 mg/kg/day, daily gavage, 4 weeks)

Conversely, UVB radiation enhances melanin synthesis by facilitating melanocyte differentiation and stimulating keratinocytes to release melanocyte-stimulating hormone (MSH), along with associated immunomodulatory factors and stem cell growth factors (92, 93)

The changes in levels of cAMP is then measured over a defined period of time, for example, by radio-immuno or protein binding assays (for example using Flashplates or a scintillation proximity assay)

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This direct delivery method also allows us to administer medications that cannot be taken orally and can be used to enhance the contrast for medical imaging