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A small molecule targeting the interaction between human papillomavirus E7 oncoprotein and cellular phosphatase PTPN14 exerts antitumoral activity in cervical cancer cells

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For the analysis of specific metabolites, the maximum and minimum values of each group were excluded to reduce the within-group variation

For instance, lysosomal dysfunction in Fabry disease, a rare X-linked lysosomal disorder characterized by a buildup of globotriaosylceramide (Gb3) due to a deficiency of the lysosomal enzyme, alpha-galactosidase (GLA), has shown a decline in mitochondrial function and mitochondrial energy metabolism in renal cells [27]

[DOI] [PMC free article] [PubMed] [Google Scholar] (164).Usman WM