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PAMPs: Pathogen-associated molecular patterns

Signaling Pathways Apoptosis Metabolic Enzyme/Protease Glutathione Peroxidase Glutathione Peroxidase Glutathione peroxidases (GPx) are a family of enzymes with the ability to reduce organic and inorganic hydroperoxides to the corresponding alcohols using glutathione or thioredoxin as an electron donor

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doi: 10.1016/j.nicl.2016.06.006 249 Orthmann-MurphyJ

This helps explain why patients with extensive surgical trauma or prolonged ischemia often develop a systemic inflammatory response that parallels septic shock, even in the absence of infection (54)