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At the molecular level, homeostasis is controlled by a neuro-endocrine-immune system network wherein LTF plays a central role, largely due to its above-mentioned ability to bind ferric ions

Sustained high cortisol levels can interfere with the negative feedback loop that ordinarily modulates the HPA axis, resulting in its overactivity

Kaijun Zhao, Tongji University, China

The translatability of ferroptosis-targeted therapies from current models to humans is thus uncertain

We reviewed and found that acupuncture can improve the symptoms of patients with PSCI by protecting the IEB, remodeling the structure of gut microbiota, inhibiting inflammation, regulating metabolic pathways and regulating the hypothalamic-pituitary-adrenal (HPA) axis (Tables 1, 2)

Pelvic Pain Feeling pain or discomfort in the lower belly area, including the pelvic zone, can be worrying