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Description

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However, several off-label pharmacologic options are being explored

Currently in NCI, she is studying the structural principles of signaling proteins, such as Bcr, c-Abl, and SHP2, and uncovering their mechanisms of proteinprotein interaction, activation, and inhibition, for drug discovery

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These peptides are primarily expressed in macrophages and polymorphonuclear leukocytes, where they contribute to innate immune defense against microbial threats