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et al., 2024d) and histotripsy ( Several natural or traditional Chinese medicine (TCM) formulations modulate HMGB1 release and ferroptosis via anti-inflammatory and antioxidative signaling

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There is also emerging evidence suggesting its benefits in preventing severe cases of COVID-19 and long COVID

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In addition, it is important to highlight that the regulation of intracellular antioxidant concentration is a double-edged sword: On the one hand, enhanced antioxidant activity represents an advantageous protection of the cells from ROS, whereas, on the other hand, the depletion of antioxidants represents an important strategy to sensitize cancer cells to chemotherapy (chemosensitization) (50)

Inflammation reduction becomes visible in some cases