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NMR spectroscopy measurements NMR spectra were recorded on a Varian 600 MHz spectrometer at 25.0 0.1 C

The biological significance of substrate inhibition: a mechanism with diverse functions

P., Matsuoka, Y., & Pae, C

Given that both APR-017 and LCS3 are involved in inhibiting the GSH synthesis metabolism pathway, we examined whether the lethal effects of APR-017 and LCS3 on VRK2-deficient cells were due to inhibition of GSH