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Munc13-4 polymorphism is associated with MAS, sJIA and systemic inflammation, while chronic TLR9 stimulation in mice develops features characteristic of MAS, including elevated serum levels of IFN, interleukin 6 (IL-6) and hepatic inflammation 10

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He also stresses the importance of consulting with a licensed healthcare provider before starting any type of injectable regimen

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If a patient is experiencing side effects from an antihypertensive medication, then another alternative should be selected