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Flumazenil versus placebo or no intervention for people with cirrhosis and hepatic encephalopathy

Later studies revealed that anti-PEG antibodies can bind to the surface of PEGylated liposomes, alter the composition of the protein corona, activate the complement system and elicit an immune response, becoming a serious problem for all PEGylated agents, including PEGylated liposomes

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McMillan, P

The frequently encountered lipid types include cationic, anionic, amphoteric, and polyethylene glycol (PEG)-derived lipids