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[6] Hamley IW

ADH1 acetaldehyde dehydrogenase 1 disulfiram may be used as a metal chelator since its metabolite DDC may form a copper complex at a 2:1 mole ratio (DDC:Cu2+)

Beside the described scavenging effect, however, oxidation of methionine residues leads to a decrease in the protective effect of A1AT as a protease inhibitor (37)