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Thus, collectively, it can be concluded that Set7/9 antagonizes Hif1 activity both under normoxic and hypoxic conditions

Searching for more class 1 genes whose promoters contain known SLIM1 binding motifs, SURE or TEBS, we identified seven additional genes ( Table 2 )

To determine the specific location, we used transiently expressed FLAG-tagged ATP6AP1 as bait, which localized almost exclusively into discrete vesicles throughout the cytosol (Fig