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A case series (GSH soap: 15 patients) reported skin lightening based on photography

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6 How They Work in the Body Glutamine as Cellular Fuel L-glutamine is particularly important in the gut and immune system, and glutamine supplementation can assist when natural production doesn't meet body demands

A pleiotropic factor played a role in immunomodulation, G-CSF, negatively associated with pro-inflammatory mediators such as TNF-, IL-23, and IL-12, was constitutively expressed at a high level in intestinal lamina propria cells both in mouse and healthy individuals, but at a relatively low level in IBD patients [27]