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The initial colonization of CRC tissues is facilitated by extracellular vesicles derived from F.n (FnEVs), which transfer the outer membrane protein FomA to cancer cells, creating a niche for bacterial adhesion and aggregation (Zheng et al., 2024)

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To address this, advanced modeling strategies based on human single-cell and spatial transcriptomics are neededsuch as human skin organoids, ex vivo skin explants, or fully immunocompetent humanized mouse modelsto dissect the true functional landscape of Vitamin D within complex signaling networks

Blood pressure often improves with sustained weight loss, though the magnitude varies with individual starting points and concurrent medications