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These mechanistic findings, together with the excellent safety profile after methanol and ethylene glycol poisoning and after an APAP overdose, suggest that fomepizole may be a promising antidote against APAP overdose that could be useful as adjunct treatment to NAC

Kidney function, hydration, medications, cystatin C and the overall clinical picture may be important when interpreting follow-up results

The positive modulation of the gut microbiota in fish in turn resulted in improvement in the growth, gut health, nutrient metabolism, immune response and disease resistance of the host (Qi et al., 2024)

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4.1.1 Local delivery of RNA-LNPs A straightforward way to bypass hepatic accumulation of LNPs is to change the administration route from intravenous delivery to other administration routes, which could shorten the delivery path and enhance accessibility to the target cells (Figure 3) (Chenthamara et al., 2019

Below, we explore the key differences between liposomal glutathione and traditional supplements, focusing on absorption and efficacy