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On the other hand, AR also utilizes NADPH to convert glucose to sorbitol, which depletes intracellular NADPH, making GSSG irreducible and promoting oxidative stress 18

Infection by SARS-CoV-2 is initiated by the binding of its fusion protein, the spike (S) protein, to the entry receptor, angiotensin-converting enzyme 2 (ACE2) 53,54,55

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However, when investigating the effect of benfotiamine and thiamine on Nrf2/ARE pathway, master regulator of cellular antioxidative response, Tapias et al

Lundsgaard AM, Kiens B (2014) Gender differences in skeletal muscle substrate metabolism - molecular mechanisms and insulin sensitivity

The Orange & Blue kept the game competitive in the first quarter but a massive second period propelled the top-ranked Bruins to the victory