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The authors administered oral Dihexa to APP/PS1 transgenic mice (a standard amyloidopathy model of Alzheimers disease) and showed that brain AngIV levels were elevated relative to wild-type after Dihexa administration, that spatial learning and memory were restored on Morris water maze testing, that hippocampal neuronal density and synaptophysin protein expression were preserved, that astrocyte and microglial activation were reduced, and that pro-inflammatory cytokines (IL-1, TNF-) decreased while anti-inflammatory IL-10 increased

Yoshitomi K., Boorman G

Injection site reactions: Pain, local tenderness , or swelling at the site of injection

functional differentiation

Equal protein concentrations (25 g) were loaded and electrophoresis was performed on SDS-PAGE (810%) under reducing conditions

The composition is just perfect, it does not stick, does not form a film, does not feel a greasy layer