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Funding This project was funded by the Vitamin Research Fund awarded to AF and provided by the University of Alberta for graduate and postdoctoral fellow research

The vitamin is a cofactor for methionine synthase, which catalyzes the conversion of homocysteine to methioninerequired for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 substrates, including DNA, RNA, hormones, proteins, and lipids

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It is a synthetic quinolinium small molecule studied as an inhibitor of nicotinamide N-methyltransferase