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Hoewel de mogelijkheid bestaat dat chronisch ethanolgebruik het risico op PCM hepatotoxiciteit in mensen vergroot, is bewijs hiervoor voornamelijk gevonden in dieren en gextrapoleerd naar mensen

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Unlike PROTACs, which rely on bifunctional molecules to recruit E3 ubiquitin ligases, molecular glues are typically small molecules that induce or stabilize interactions between target proteins and ubiquitin ligases, thereby promoting selective protein degradation through the ubiquitin-proteasome system