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Published cases improved after dose reduction

This demonstrates the critical role of the CHAC2-NRF2 signaling pathway in protecting against oxidative stress and highlights CHAC2 as a potential therapeutic target for mitigating APAP-induced liver damage (Zhai et al., 2022)

Nimalaratne C, Savard P, Gauthier SF, Schieber A, Wu J (2015) Bioaccessibility and digestive stability of carotenoids in cooked eggs studied using a dynamic in vitro gastrointestinal model

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Finally, the proteins were visualized by applying Super Signal West Femto Chemiluminescent Substrate (Thermo Scientific) to the membranes, followed by detection in the molecular imager ChemiDoc MP and quantification of the detected bands using the Image Lab software (Bio-Rad Laboratories)

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