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4-Hydroxyphenylacetic acid prevents acute APAP-induced liver injury by increasing phase II and antioxidant enzymes in mice

Ein besonders aufschlussreiches Experiment verwendete Kollagen-Wundauflagen mit inkorporiertem GHK (PIC-Dressings)

References Edgar, S

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Cell Culture Human hepatocyte HepG2 cells were purchased from the Cell Culture Center of the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College

-glutamyl kinase (GK) encoded by PRO1 in eukaryotes or proB in prokaryotes, the first enzyme in proline biosynthetic pathway, catalyzes the formation of intermediate -glutamyl phosphate, which if accumulated could partially react with cysteine to generate -GC, and then Gsh2 adds glycine to -GC to form GSH