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Ipamorelins ability to amplify these pulses without flattening them into a sustained elevation distinguishes it from approaches that produce continuous GH exposure, and has informed experimental design in studies seeking to model physiologically relevant GH stimulation.

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Ethics declarations Conflict of Interest The authors declare no conflicts of interest relevant to this manuscript

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and S.v.H.) independently using MEDLINE and PubMed with the MeSH terms: nutraceuticals, dietary supplements, herbal drug, heart failure, muscle wasting and sarcopenia