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Hence, substitution of glutamate with the longer, positively charged lysine probably causes steric hindrance that disrupts stable substrate binding and/or slows substrate release due to enhanced electrostatic interactions between the transporter and the polar side chains of porphyrin substrates

doi: 10.1056/NEJM198512053132327 19 ParmianiG

Effect of fat content on the digestibility and bioaccessibility of cocoa polyphenol by an in vitro digestion model

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2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells