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Marcucci KA, Pearce RE, Crespi C, Steimel DT, Leeder JS, Gaedigk A

Sequencing data from pooled lanes were demultiplexed, and after a default quality-filtering step (using FastQC_v.0.10.1), they were recorded in FastQ files representing raw data

Additional Information For dilution, use non-chlorinated water or water left to settle for 12 hours in an open container.

While the workflow has been systematically applied across multiple patients, this case exemplifies how exome sequencing, PRS calculation, and biochemical profiling can converge into a consolidated report and ultimately a targeted clinical plan

Through this cycling, Arfs recruit coat proteins (e.g., clathrin), coat adaptor proteins, cargoes, lipid-modifying enzymes, and cytoskeletal regulators to budding vesicles [112]

CORE has conducted a wide range of research and consultancy works in collaboration with government institutions, private sector, international donor agencies and the media