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After DNA virus infection, host cells release Mn 2+ from membrane organelles to cytosol, which is accumulated to activate cGAS-STING signaling pathway to induce IRF3 phosphorylation, activate NF-B pathway and promote IFN-I production for antiviral effects

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Overexpression of long non-coding RNA, TMEM161B-AS1 drives malignant behavior and TMZ-resistance by regulating FANCD2 and CD44 via hsa-miR-27a-3p sponging [78], further highlighting the intricate role of miRNAs in ferroptosis regulation