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Several FDA-approved medications, such as sorafenib, salazosulfapyridine (SAS), and acetaminophen, have been demonstrated to induce ferroptosis in a variety of cancerous and non-cancerous cell types by inhibiting the system Xc or GSH [130,131,132]

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Schrodinger, LLC

R.ChenX

Journal title Microbiology Spectrum (2021) 9, e0025721

In another related study, briefly outlined above, malignant cells, such as those found in melanoma, frequently spread locally via the lymphatic system before being disseminated systemically through the bloodstream