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One technique to fully recover samples is removal of the organic solvent by evaporation followed by addition of water (to dissolve DMSO) and cryodesiccation to remove both DMSO and water

Ann Neurol (2010) 67(4):45261

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The following summarizes mechanisms observed in preclinical settings only

2.11 RNA-seq analysis The cell samples were harvested with RNAiso Plus reagent immediately after 24 h of treatment with blank medium or medium containing 15 mg/dL UA