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the dose should be adjusted or discontinued if seizure activity increases

Nat Rev Mol Cell Biol 19:713730

PMID 16981011

JC-1 dye accumulates in active mitochondria, leading to the formation of J-aggregates with red/orange fluorescence emission at 590 nm, while under conditions of mitochondrial depolarization or low potentials, JC-1 exists as J-monomers emitting a green fluorescence at 525 nm

Mauvais-Jarvis F, Lange CA, Levin ER

However, studies on the effect of taking vitamin D supplements on migraine-related parameters, including intensity and duration, have been reported differently