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They should be referred for genetic counseling

Altenberg, B

Salim Kanaan, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Research is ongoing, and more human studies are needed

The authors also note that long-term studies will be necessary to better understand potential toxicity and tissue-specific effects

Therefore, while our data demonstrate robust adipose tissue remodeling following Retatrutide treatment, they do not by themselves establish direct cell-autonomous effects on adipocytes or adipose-resident immune cells