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Publisher: Springer Verlag 2010 Data Mining Patterns: New Methods and Applications (2008) Chapter: Discovery of Latent Patterns with Hierarchical Bayesian Mixed-Membership Models and the Issue of Model Choice Authors: Airoldi, E

Given the brains unique susceptibility to proteotoxic stress, owing to its post-mitotic neuronal population, high metabolic demand, and reliance on precise proteome regulation, UPS integrity is indispensable for neuronal survival