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Active forms such as methylcobalamin and 5-MTHF help ensure the body can efficiently utilize these essential nutrients, particularly in individuals with impaired methylation pathways

Quality assessment and risk of bias In line with PRISMA guidelines, the assessment of methodological quality was conducted to evaluate the strength of evidence, recognising that methodological limitations may introduce bias

Pernicious Anemia : This is a specific type of anemia associated with vitamin B12 deficiency, characterized by a reduction in the number of healthy red blood cells

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CPT 20220 represents a percutaneous biopsy of a superficial bone site, meaning the bone can be accessed without cutting through deep layers of muscle or complex anatomical structures

Together, these nutrients may contribute to a healthier cardiovascular profile