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Description

The destruction or reduction of TJ proteins can disrupt the gastrointestinal mucosal barrier, causing UC and other intestinal disorders

Gastroenterology 96:795803 Bell CJ, Gall DG, Wallace JL (1995) Disruption of colonic electrolyte transport in experimental colitis

The SGLT-2 inhibitor empagliflozin improves myocardial strain, reduces cardiac fibrosis and pro-inflammatory cytokines in non-diabetic mice treated with doxorubicin