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Glutathione peroxidase 4 (Gpx4) is a key enzyme in suppressing ferroptosis by reducing phospholipid hydroperoxides in membranes

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doi: 10.1016/j.bbrc.2022.06.099

Together, these findings classify AcEO and 1N2PE as class 4 xenobiotics (low toxicity) (OECD, 2001)