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Additionally, Sal alleviates MI size, myocardial hypertrophy, and systolic dysfunction through the CAN/NFATc3/BMHC pathway, significantly improving myocardial cell remodeling post-MI ( 6.1.6 -caryophyllene (BCP) In recent years, certain G protein-coupled receptors (GPCRs) in the endocannabinoid system, particularly cannabinoid type 1 and type 2 receptors (CB1 and CB2), have emerged as significant therapeutic targets for cardiac protection