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neoformans infection, contributing to its survival within macrophages, facilitating invasion of the central nervous system, and promoting colonization of host tissues ( 4 Potential therapeutic small molecules The majority of compound libraries have been created to maximize their drug-like qualities with regard to mammalian targets and physiology, while antifungal drugs require special physicochemical properties, partly because these molecules must be able to pass through the fungal cell wall

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Each pathway responds differently to temperature changes, creating complex stability profiles that vary between peptide compounds