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1.2 Biochemical mechanisms of TMA production Most of the TMA is synthesized in the intestine (colon) by the action of some anaerobic commensal gut bacteria containing choline- (or carnitine-) TMA lyase, an enzyme consisting of two units: a catalytic unit (CutC) and its activating enzyme (CutD) ( etc .), betaine, and L-carnitine and its metabolite -butyrobetaine (GBB), releasing TMA after the cleavage of the carbon (C)nitrogen (N) bond of choline/carnitine (Zhu et al., 2014)

L-Carnitine 50 mg/ml Oral Liquid is used as a supplement or medication to increase L-Carnitine levels in patients who have a deficiency or require supplemental L-Carnitine for certain health conditions

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Lenski, M

Liu X, Lin J, Zhang H, Khan NU, Zhang J, Tang X, et al

& Ishitsuka, H