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10.1016/j.expneurol.2020.113356 82 PfeiferJ

The incorporation of these technologies is likely to improve cardiovascular medicine and accelerate the change from molecular mechanisms to clinical practice, ultimately realizing the 4P vision of precision medicine: Predictive, Preventive, Personalized, and Participatory

At this time, flumazenil is not Food and Drug Administration-approved nor guideline-recommended (AASLD 2014) for the treatment of HE, though it is mentioned as possible therapy in select cases pending further study