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Corosolic acid sensitizes ferroptosis by upregulating HERPUD1 in liver cancer cells

It is known that autophagy is defective in dopaminergic neurons in the SN, as observed in post-mortem brains of patients and certain models of PD like 6-OHDA and rotenone-induced models, which show suppression of mTOR, a key enhancer of autophagy (Grassi et al., 2018)

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Mullenbach, J., Wiegreffe, S., Duke, J., Sun, J

Instead, research suggests it works by inhibiting Hepatocyte Growth Factor Activator Inhibitor (HAI-1), an enzyme that normally limits HGF activity

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