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Molecular mechanism of the ichthyosis pathology of ChanarinDorfman syndrome: stimulation of PNPLA1-catalyzed - O -acylceramide production by ABHD5

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Specifically, this paper discusses the application of mitochondrial-derived peptides, including MOTS-c, in the treatment of diseases and anticipates the future development direction of MOTS-c combining synthetic biology to provide new ideas on how it can be developed and applied

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