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however, only in male mice, suggesting that this treatment may not be effective in the female population and further emphasizing the importance of sex differences in targeted treatments [107, 108]

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doi: 10.1016/j.mehy.2011.03.030 96 LacerdaEMGeraghtyKKingdonCCPallaLNaculL

61 The intracerebroventricular (ICV) administration of STZ elicits a distinct influence on the central nervous system (CNS) without noticeable effects on peripheral regions

NACET penetrates mitochondrial membranes to restore redox balance, protecting the electron transport chain from ROS damage

doi: 10.1016/j.cell.2004.07.013 145 HofsethLJSinghUPSinghNPNagarkattiMNagarkattiPS