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The increase in unscheduled glycolysis may lead to DNA damage at least partially by reducing the dNTP pool by O-GlcNAcylation of ribonucleotide reductase catalytic subunit M1(RRM1), which may subsequently cause adaptive DNA mutations to maintain cell survival [10]

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At a certain level, ROS works as an indicator molecule for activating acclimatory/protection responses through transduction pathways, where H 2 O 2 acts as a secondary messenger 12,13

Variance among all groups was not statistically different

The presence of methyl groups in DNA chains is necessary for the formation of chromosome structure and the regulation of gene transcription (Jorgensen and Ro, 2019

(Singapore: Springer Singapore), 219245