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Jiang Z

An increasing body of literature indicates that epigenetic modifications contribute substantially to the progression of DN, primarily by activating mechanisms related to oxidative stress

Alme, Katinka Nordheim

It facilitates tumor cell susceptibility to ferroptosis through the suppression of SLC7A11 gene transcription and the activation of ZEB1 activity

Research has shown that antioxidant interventions, including vitamin E, deferoxamine (DFO), or Fer-1, can alleviate ferroptosis in T cells lacking GPX4 ( Figure 2 ) (114)